PDB 5zaf

PDB Information

PDB5ZAF
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceHomo sapiens
Primary Citation
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
Buckley, B.J., Aboelela, A., Minaei, E., Jiang, L.X., Xu, Z., Ali, U., Fildes, K., Cheung, C.Y., Cook, S.M., Johnson, D.C., Bachovchin, D.A., Cook, G.M., Apte, M., Huang, M., Ranson, M., Kelso, M.J.
J. Med. Chem.
HeaderHydrolase
Released2018-02-07
Resolution1.650
CATH Insert Date23 Dec, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
U 23 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5zafU01 26 Dec, 2018 Holding pen
5zafU02 26 Dec, 2018 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator
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