PDB 5yqx

PDB Information

PDB5YQX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.
Xue, X., Zhang, Y., Wang, C., Zhang, M., Xiang, Q., Wang, J., Wang, A., Li, C., Zhang, C., Zou, L., Wang, R., Wu, S., Lu, Y., Chen, H., Ding, K., Li, G., Xu, Y.
Eur.J.Med.Chem.
HeaderTranscription
Released2017-11-08
Resolution1.820
CATH Insert Date16 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5yqxA01 28 Feb, 2019 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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