PDB 5yqn

PDB Information

PDB5YQN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells.
Yang, L.L., Wang, H.L., Zhong, L., Yuan, C., Liu, S.Y., Yu, Z.J., Liu, S., Yan, Y.H., Wu, C., Wang, Y., Wang, Z., Yu, Y., Chen, Q., Li, G.B.
Eur J Med Chem
HeaderHydrolase/Hydrolase Inhibitor
Released2017-11-07
Resolution1.600
CATH Insert Date16 Dec, 2018

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
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