PDB 5y8z

PDB Information

PDB5Y8Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)
Zhang, M., Zhang, Y., Song, M., Xue, X., Wang, J., Wang, C., Zhang, C., Li, C., Xiang, Q., Zou, L., Wu, X., Wu, C., Dong, B., Xue, W., Zhou, Y., Chen, H., Wu, D., Ding, K., Xu, Y.
J. Med. Chem.
HeaderTranscription
Released2017-08-22
Resolution1.840
CATH Insert Date06 Jul, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5y8zA01 19 Jul, 2018 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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