PDB 5xzb

PDB Information

PDB5XZB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice.
Vincent, J., Adura, C., Gao, P., Luz, A., Lama, L., Asano, Y., Okamoto, R., Imaeda, T., Aida, J., Rothamel, K., Gogakos, T., Steinberg, J., Reasoner, S., Aso, K., Tuschl, T., Patel, D.J., Glickman, J.F., Ascano, M.
Nat Commun
HeaderImmune System/Inhibitor
Released2017-07-12
Resolution2.130
CATH Insert Date14 Nov, 2017

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
E 14 Nov, 2017 Rejected
F 14 Nov, 2017 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5xzbA01 10 Dec, 2017 1.10.1410.40 Assigned
5xzbA02 10 Dec, 2017 3.30.460.90 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8C6L5 CGAS_MOUSE Mus musculus Cyclic GMP-AMP synthase