PDB 5xsu

PDB Information

PDB5XSU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
Chen, X., Huan, X., Liu, Q., Wang, Y., He, Q., Tan, C., Chen, Y., Ding, J., Xu, Y., Miao, Z., Yang, C.
Eur J Med Chem
HeaderTransferase/Transferase Inhibitor
Released2017-06-15
Resolution2.400
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5xsuA01 28 Jun, 2018 Holding pen
5xsuA02 28 Jun, 2018 3.90.228.10 Assigned
5xsuB01 28 Jun, 2018 Holding pen
5xsuB02 28 Jun, 2018 3.90.228.10 Assigned
5xsuC01 28 Jun, 2018 Holding pen
5xsuC02 28 Jun, 2018 3.90.228.10 Assigned
5xsuD01 28 Jun, 2018 Holding pen
5xsuD02 28 Jun, 2018 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1