PDB 5xqx

PDB Links
Overview

PDB Information

PDB	5XQX
Method	X-RAY DIFFRACTION
Host Organism	unidentified baculovirus
Gene Source	Homo sapiens
Primary Citation	Discovery of potent and selective CDK8 inhibitors through FBDD approach Han, X., Jiang, M., Zhou, C., Zhou, Z., Xu, Z., Wang, L., Mayweg, A.V., Niu, R., Jin, T.G., Yang, S. Bioorg. Med. Chem. Lett.
Header	Transferase
Released	2017-06-07
Resolution	2.300
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5xqx

5xqx

PDB 5xqx

Image of CATH 5xqxA

5xqxA

PDB Chain 5xqxA

Image of CATH 5xqxB

5xqxB

PDB Chain 5xqxB

Image of CATH 5xqxA01

5xqxA01

CATH Domain 5xqxA01

Image of CATH 5xqxA02

5xqxA02

CATH Domain 5xqxA02

Image of CATH 5xqxB01

5xqxB01

CATH Domain 5xqxB01

Image of CATH 5xqxB02

5xqxB02

CATH Domain 5xqxB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5xqxA01	10 Dec, 2017	3.30.200.20	Assigned
5xqxA02	10 Dec, 2017	1.10.510.10	Assigned
5xqxB01	10 Dec, 2017	1.10.472.10	Assigned
5xqxB02	10 Dec, 2017	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8