PDB Information

PDB5XLT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design
Niu, L., Wang, Y., Wang, C., Wang, Y., Jiang, X., Ma, L., Wu, C., Yu, Y., Chen, Q.
Biochem. Biophys. Res. Commun.
HeaderCell Cycle
Released2017-05-11
Resolution2.810
CATH Insert Date14 Nov, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5xltA01 10 Dec, 2017 3.40.50.1440 Assigned
5xltA02 10 Dec, 2017 3.30.1330.20 Assigned
5xltA03 10 Dec, 2017 1.10.287.600 Assigned
5xltB01 10 Dec, 2017 3.40.50.1440 Assigned
5xltB02 10 Dec, 2017 3.30.1330.20 Assigned
5xltB03 10 Dec, 2017 1.10.287.600 Assigned
5xltC01 10 Dec, 2017 3.40.50.1440 Assigned
5xltC02 10 Dec, 2017 3.30.1330.20 Assigned
5xltC03 10 Dec, 2017 1.10.287.600 Assigned
5xltD01 10 Dec, 2017 3.40.50.1440 Assigned
5xltD02 10 Dec, 2017 3.30.1330.20 Assigned
5xltD03 10 Dec, 2017 1.10.287.600 Assigned
5xltE01 10 Dec, 2017 6.10.280.30 Assigned
5xltF01 10 Dec, 2017 3.40.50.11480 Assigned
5xltF02 10 Dec, 2017 3.30.470.20 Assigned
5xltF03 10 Dec, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain