PDB 5x69
PDB Information
| PDB | 5X69 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem.
|
| Header | Transferase |
| Released | 2017-02-21 |
| Resolution | 2.690 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (13)
5x69
PDB 5x69
5x69A
PDB Chain 5x69A
5x69B
PDB Chain 5x69B
5x69C
PDB Chain 5x69C
5x69D
PDB Chain 5x69D
5x69E
PDB Chain 5x69E
5x69F
PDB Chain 5x69F
5x69A00
CATH Domain 5x69A00
5x69B00
CATH Domain 5x69B00
5x69C00
CATH Domain 5x69C00
5x69D00
CATH Domain 5x69D00
5x69E00
CATH Domain 5x69E00
5x69F00
CATH Domain 5x69F00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Chopped |
| D | 14 Nov, 2017 | Chopped |
| E | 14 Nov, 2017 | Chopped |
| F | 14 Nov, 2017 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5x69A00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x69B00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x69C00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x69D00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x69E00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
| 5x69F00 | 10 Dec, 2017 | 3.30.572.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |