PDB 5x1w
PDB Information
| PDB | 5X1W |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
Bioorg. Med. Chem.
|
| Header | Transferase |
| Released | 2017-01-27 |
| Resolution | 3.000 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (17)
5x1w
PDB 5x1w
5x1wA
PDB Chain 5x1wA
5x1wB
PDB Chain 5x1wB
5x1wC
PDB Chain 5x1wC
5x1wD
PDB Chain 5x1wD
5x1wA01
CATH Domain 5x1wA01
5x1wA02
CATH Domain 5x1wA02
5x1wA03
CATH Domain 5x1wA03
5x1wB01
CATH Domain 5x1wB01
5x1wB02
CATH Domain 5x1wB02
5x1wB03
CATH Domain 5x1wB03
5x1wC01
CATH Domain 5x1wC01
5x1wC02
CATH Domain 5x1wC02
5x1wC03
CATH Domain 5x1wC03
5x1wD01
CATH Domain 5x1wD01
5x1wD02
CATH Domain 5x1wD02
5x1wD03
CATH Domain 5x1wD03
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Chopped |
| D | 14 Nov, 2017 | Chopped |
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5x1wA01 | 10 Dec, 2017 | 3.40.1380.20 | Assigned |
| 5x1wA02 | 10 Dec, 2017 | 3.20.20.60 | Assigned |
| 5x1wA03 | 10 Dec, 2017 | Holding pen | |
| 5x1wB01 | 10 Dec, 2017 | 3.40.1380.20 | Assigned |
| 5x1wB02 | 10 Dec, 2017 | 3.20.20.60 | Assigned |
| 5x1wB03 | 10 Dec, 2017 | Holding pen | |
| 5x1wC01 | 10 Dec, 2017 | 3.40.1380.20 | Assigned |
| 5x1wC02 | 10 Dec, 2017 | 3.20.20.60 | Assigned |
| 5x1wC03 | 10 Dec, 2017 | Holding pen | |
| 5x1wD01 | 10 Dec, 2017 | 3.40.1380.20 | Assigned |
| 5x1wD02 | 10 Dec, 2017 | 3.20.20.60 | Assigned |
| 5x1wD03 | 10 Dec, 2017 | Holding pen |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P14618 | KPYM_HUMAN | Homo sapiens | Pyruvate kinase PKM |
| P14618 | KPYM_HUMAN | Homo sapiens | Pyruvate kinase PKM |
| P14618 | KPYM_HUMAN | Homo sapiens | Pyruvate kinase PKM |
| P14618 | KPYM_HUMAN | Homo sapiens | Pyruvate kinase PKM |
