PDB Information

PDB5X02
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells withFLT3mutations.
Yamaura, T., Nakatani, T., Uda, K., Ogura, H., Shin, W., Kurokawa, N., Saito, K., Fujikawa, N., Date, T., Takasaki, M., Terada, D., Hirai, A., Akashi, A., Chen, F., Adachi, Y., Ishikawa, Y., Hayakawa, F., Hagiwara, S., Naoe, T., Kiyoi, H.
Blood
HeaderTransferase/Transferase Inihibitor
Released2017-01-19
Resolution2.400
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5x02A01 28 Jun, 2018 3.30.200.20 Assigned
5x02A02 28 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P36888 FLT3_HUMAN Homo sapiens Receptor-type tyrosine-protein kinase FLT3
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