PDB 5wfq

PDB Links
Overview

PDB Information

PDB	5WFQ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling. Burns, M.C., Howes, J.E., Sun, Q., Little, A.J., Camper, D.V., Abbott, J.R., Phan, J., Lee, T., Waterson, A.G., Rossanese, O.W., Fesik, S.W. Anal. Biochem.
Header	Signaling Protein
Released	2017-07-12
Resolution	2.260
CATH Insert Date	03 Jun, 2018

PDB Images (8)

Image of CATH 5wfq

5wfq

PDB 5wfq

Image of CATH 5wfqN

5wfqN

PDB Chain 5wfqN

Image of CATH 5wfqQ

5wfqQ

PDB Chain 5wfqQ

Image of CATH 5wfqR

5wfqR

PDB Chain 5wfqR

Image of CATH 5wfqN01

5wfqN01

CATH Domain 5wfqN01

Image of CATH 5wfqN02

5wfqN02

CATH Domain 5wfqN02

Image of CATH 5wfqQ00

5wfqQ00

CATH Domain 5wfqQ00

Image of CATH 5wfqR00

5wfqR00

CATH Domain 5wfqR00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
N	03 Jun, 2018	Chopped
Q	03 Jun, 2018	Chopped
R	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5wfqN01	28 Jun, 2018	1.20.870.10	Assigned
5wfqN02	28 Jun, 2018	1.10.840.10	Assigned
5wfqQ00	28 Jun, 2018	3.40.50.300	Assigned
5wfqR00	28 Jun, 2018	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1