PDB 5wfo

PDB Links
Overview

PDB Information

PDB	5WFO
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling. Burns, M.C., Howes, J.E., Sun, Q., Little, A.J., Camper, D.V., Abbott, J.R., Phan, J., Lee, T., Waterson, A.G., Rossanese, O.W., Fesik, S.W. Anal. Biochem.
Header	Signaling Protein
Released	2017-07-12
Resolution	1.990
CATH Insert Date	03 Jun, 2018

PDB Images (8)

Image of CATH 5wfo

5wfo

PDB 5wfo

Image of CATH 5wfoN

5wfoN

PDB Chain 5wfoN

Image of CATH 5wfoQ

5wfoQ

PDB Chain 5wfoQ

Image of CATH 5wfoR

5wfoR

PDB Chain 5wfoR

Image of CATH 5wfoN01

5wfoN01

CATH Domain 5wfoN01

Image of CATH 5wfoN02

5wfoN02

CATH Domain 5wfoN02

Image of CATH 5wfoQ00

5wfoQ00

CATH Domain 5wfoQ00

Image of CATH 5wfoR00

5wfoR00

CATH Domain 5wfoR00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
N	03 Jun, 2018	Chopped
Q	03 Jun, 2018	Chopped
R	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5wfoN01	28 Jun, 2018	1.20.870.10	Assigned
5wfoN02	28 Jun, 2018	1.10.840.10	Assigned
5wfoQ00	28 Jun, 2018	3.40.50.300	Assigned
5wfoR00	28 Jun, 2018	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1