PDB 5vo6

PDB Information

PDB5VO6
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.
Hynes, J., Wu, H., Kempson, J., Duan, J.J., Lu, Z., Jiang, B., Stachura, S., Tokarski, J.S., Sack, J.S., Khan, J.A., Lippy, J.S., Zhang, R.F., Pitt, S., Shen, G., Gillooly, K., McIntyre, K., Carter, P.H., Barrish, J.C., Nadler, S.G., Salter-Cid, L.M., Fura, A., Schieven, G.L., Pitts, W.J., Wrobleski, S.T.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Inhibitor
Released2017-05-02
Resolution2.650
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5vo6A01 10 Dec, 2017 3.30.200.20 Assigned
5vo6A02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
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