Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase delta (PI3K delta ) Inhibitor for the Treatment of Immunological Disorders.
Liu, Q., Shi, Q., Marcoux, D., Batt, D.G., Cornelius, L., Qin, L.Y., Ruan, Z., Neels, J., Beaudoin-Bertrand, M., Srivastava, A.S., Li, L., Cherney, R.J., Gong, H., Watterson, S.H., Weigelt, C., Gillooly, K.M., McIntyre, K.W., Xie, J.H., Obermeier, M.T., Fura, A., Sleczka, B., Stefanski, K., Fancher, R.M., Padmanabhan, S., Rp, T., Kundu, I., Rajareddy, K., Smith, R., Hennan, J.K., Xing, D., Fan, J., Levesque, P.C., Ruan, Q., Pitt, S., Zhang, R., Pedicord, D., Pan, J., Yarde, M., Lu, H., Lippy, J., Goldstine, C., Skala, S., Rampulla, R.A., Mathur, A., Gupta, A., Arunachalam, P.N., Sack, J.S., Muckelbauer, J.K., Cvijic, M.E., Salter-Cid, L.M., Bhide, R.S., Poss, M.A., Hynes, J., Carter, P.H., Macor, J.E., Ruepp, S., Schieven, G.L., Tino, J.A.
J. Med. Chem.