PDB 5vl7

PDB Links
Overview

PDB Information

PDB	5VL7
Method	X-RAY DIFFRACTION
Host Organism	Cricetulus griseus
Gene Source	Homo sapiens
Primary Citation	Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists. Zhang, Y., Ultsch, M., Skelton, N.J., Burdick, D.J., Beresini, M.H., Li, W., Kong-Beltran, M., Peterson, A., Quinn, J., Chiu, C., Wu, Y., Shia, S., Moran, P., Di Lello, P., Eigenbrot, C., Kirchhofer, D. Nat. Struct. Mol. Biol.
Header	Hydrolase
Released	2017-04-25
Resolution	3.500
CATH Insert Date	14 Nov, 2017

PDB Images (12)

Image of CATH 5vl7

5vl7

PDB 5vl7

Image of CATH 5vl7A

5vl7A

PDB Chain 5vl7A

Image of CATH 5vl7B

5vl7B

PDB Chain 5vl7B

Image of CATH 5vl7H

5vl7H

PDB Chain 5vl7H

Image of CATH 5vl7L

5vl7L

PDB Chain 5vl7L

Image of CATH 5vl7A01

5vl7A01

CATH Domain 5vl7A01

Image of CATH 5vl7B01

5vl7B01

CATH Domain 5vl7B01

Image of CATH 5vl7B02

5vl7B02

CATH Domain 5vl7B02

Image of CATH 5vl7H01

5vl7H01

CATH Domain 5vl7H01

Image of CATH 5vl7H02

5vl7H02

CATH Domain 5vl7H02

Image of CATH 5vl7L01

5vl7L01

CATH Domain 5vl7L01

Image of CATH 5vl7L02

5vl7L02

CATH Domain 5vl7L02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
H	14 Nov, 2017	Chopped
L	14 Nov, 2017	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5vl7A01	10 Dec, 2017	3.30.70.80	Assigned
5vl7B01	04 May, 2018	3.40.50.200	Assigned
5vl7B02	04 May, 2018	2.60.120.690	Assigned
5vl7H01	10 Dec, 2017		Holding pen
5vl7H02	10 Dec, 2017	2.60.40.10	Assigned
5vl7L01	10 Dec, 2017	2.60.40.10	Assigned
5vl7L02	10 Dec, 2017	2.60.40.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9