PDB Information

PDB5VGI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.
Chen, Y.K., Bonaldi, T., Cuomo, A., Del Rosario, J.R., Hosfield, D.J., Kanouni, T., Kao, S.C., Lai, C., Lobo, N.A., Matuszkiewicz, J., McGeehan, A., O'Connell, S.M., Shi, L., Stafford, J.A., Stansfield, R.K., Veal, J.M., Weiss, M.S., Yuen, N.Y., Wallace, M.B.
ACS Med Chem Lett
HeaderOxidoreductase/Inhibitor
Released2017-04-11
Resolution2.070
CATH Insert Date14 Nov, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5vgiA01 10 Dec, 2017 2.60.120.650 Assigned
5vgiB01 10 Dec, 2017 2.60.120.650 Assigned
5vgiC01 10 Dec, 2017 2.60.120.650 Assigned
5vgiD01 10 Dec, 2017 2.60.120.650 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A