PDB 5vfi

PDB Information

PDB5VFI
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera
Gene SourceHomo sapiens
Primary Citation
Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.
Crawford, J.J., Johnson, A.R., Misner, D.L., Belmont, L.D., Castanedo, G., Choy, R., Coraggio, M., Dong, L., Eigenbrot, C., Erickson, R., Ghilardi, N., Hau, J., Katewa, A., Kohli, P.B., Lee, W., Lubach, J.W., McKenzie, B.S., Ortwine, D.F., Schutt, L., Tay, S., Wei, B., Reif, K., Liu, L., Wong, H., Young, W.B.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2017-04-07
Resolution1.590
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5vfiA01 28 Jun, 2018 3.30.200.20 Assigned
5vfiA02 28 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK