PDB Information

PDB5V4X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators.
Cheruvallath, Z.S., Gwaltney, S.L., Sabat, M., Tang, M., Wang, H., Jennings, A., Hosfield, D., Lee, B., Wu, Y., Halkowycz, P., Grimshaw, C.E.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Activator
Released2017-03-10
Resolution2.080
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5v4xA01 10 Dec, 2017 3.40.367.20 Assigned
5v4xA02 10 Dec, 2017 3.30.420.40 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P35557 HXK4_HUMAN Homo sapiens Glucokinase
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