PDB Information

PDB5UUP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1.
Jenson, J.M., Ryan, J.A., Grant, R.A., Letai, A., Keating, A.E.
Elife
HeaderApoptosis
Released2017-02-17
Resolution1.730
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5uupA00 10 Dec, 2017 1.10.437.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16548 B2LA1_HUMAN Homo sapiens Bcl-2-related protein A1