PDB Information

PDB5UO2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
Cinelli, M.A., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-01-31
Resolution1.950
CATH Insert Date21 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 May, 2017 Chopped
B 22 May, 2017 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5uo2A01 06 Nov, 2017 3.90.340.10 Assigned
5uo2A02 06 Nov, 2017 3.90.440.10 Assigned
5uo2A03 06 Nov, 2017 3.90.1230.10 Assigned
5uo2B01 06 Nov, 2017 3.90.340.10 Assigned
5uo2B02 06 Nov, 2017 3.90.440.10 Assigned
5uo2B03 06 Nov, 2017 3.90.1230.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29475 NOS1_HUMAN Homo sapiens Nitric oxide synthase, brain
P29475 NOS1_HUMAN Homo sapiens Nitric oxide synthase, brain
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