PDB Information

PDB5UD7
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
Sudom, A., Talreja, S., Danao, J., Bragg, E., Kegel, R., Min, X., Richardson, J., Zhang, Z., Sharkov, N., Marcora, E., Thibault, S., Bradley, J., Wood, S., Lim, A.C., Chen, H., Wang, S., Foltz, I.N., Sambashivan, S., Wang, Z.
J. Biol. Chem.
HeaderSignaling Protein
Released2016-12-23
Resolution2.200
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped
E 03 Jun, 2018 Chopped
F 03 Jun, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5ud7A00 28 Jun, 2018 2.60.40.10 Assigned
5ud7B00 28 Jun, 2018 2.60.40.10 Assigned
5ud7C00 28 Jun, 2018 2.60.40.10 Assigned
5ud7D00 28 Jun, 2018 2.60.40.10 Assigned
5ud7E00 28 Jun, 2018 2.60.40.10 Assigned
5ud7F00 28 Jun, 2018 2.60.40.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
Q9NZC2 TREM2_HUMAN Homo sapiens Triggering receptor expressed on myeloid cells 2
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