PDB 5u00

PDB Links
Overview

PDB Information

PDB	5U00
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders. Gomez, L., Massari, M.E., Vickers, T., Freestone, G., Vernier, W., Ly, K., Xu, R., McCarrick, M., Marrone, T., Metz, M., Yan, Y.G., Yoder, Z.W., Lemus, R., Broadbent, N.J., Barido, R., Warren, N., Schmelzer, K., Neul, D., Lee, D., Andersen, C.B., Sebring, K., Aertgeerts, K., Zhou, X., Tabatabaei, A., Peters, M., Breitenbucher, J.G. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-11-22
Resolution	1.410
CATH Insert Date	07 May, 2017

PDB Images (9)

Image of CATH 5u00

5u00

PDB 5u00

Image of CATH 5u00A

5u00A

PDB Chain 5u00A

Image of CATH 5u00B

5u00B

PDB Chain 5u00B

Image of CATH 5u00C

5u00C

PDB Chain 5u00C

Image of CATH 5u00D

5u00D

PDB Chain 5u00D

Image of CATH 5u00A00

5u00A00

CATH Domain 5u00A00

Image of CATH 5u00B00

5u00B00

CATH Domain 5u00B00

Image of CATH 5u00C00

5u00C00

CATH Domain 5u00C00

Image of CATH 5u00D00

5u00D00

CATH Domain 5u00D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Chopped
D	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5u00A00	22 May, 2017	1.10.1300.10	Assigned
5u00B00	22 May, 2017	1.10.1300.10	Assigned
5u00C00	22 May, 2017	1.10.1300.10	Assigned
5u00D00	22 May, 2017	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase
O00408	PDE2A_HUMAN	Homo sapiens	cGMP-dependent 3',5'-cyclic phosphodiesterase