Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
Harris, P.A., Berger, S.B., Jeong, J.U., Nagilla, R., Bandyopadhyay, D., Campobasso, N., Capriotti, C.A., Cox, J.A., Dare, L., Dong, X., Eidam, P.M., Finger, J.N., Hoffman, S.J., Kang, J., Kasparcova, V., King, B.W., Lehr, R., Lan, Y., Leister, L.K., Lich, J.D., MacDonald, T.T., Miller, N.A., Ouellette, M.T., Pao, C.S., Rahman, A., Reilly, M.A., Rendina, A.R., Rivera, E.J., Schaeffer, M.C., Sehon, C.A., Singhaus, R.R., Sun, H.H., Swift, B.A., Totoritis, R.D., Vossenkamper, A., Ward, P., Wisnoski, D.D., Zhang, D., Marquis, R.W., Gough, P.J., Bertin, J.
J. Med. Chem.
