PDB Information

PDB5TVS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The small molecule JIB-04 disrupts O2 binding in the Fe-dependent histone demethylase KDM4A/JMJD2A.
Cascella, B., Lee, S.G., Singh, S., Jez, J.M., Mirica, L.M.
Chem. Commun. (Camb.)
HeaderOxidoreductase
Released2016-11-09
Resolution2.750
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5tvsA01 22 May, 2017 2.60.120.650 Assigned
5tvsB01 22 May, 2017 2.60.120.650 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A