PDB Information

PDB5TTW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.
Barnash, K.D., The, J., Norris-Drouin, J.L., Cholensky, S.H., Worley, B.M., Li, F., Stuckey, J.I., Brown, P.J., Vedadi, M., Arrowsmith, C.H., Frye, S.V., James, L.I.
ACS Comb Sci
HeaderTranscription Regulator/Inhibitor
Released2016-11-04
Resolution1.740
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Rejected
C 08 May, 2017 Chopped
D 08 May, 2017 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ttwA00 14 Dec, 2017 2.130.10.10 Assigned
5ttwC00 14 Dec, 2017 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75530 EED_HUMAN Homo sapiens Polycomb protein EED
O75530 EED_HUMAN Homo sapiens Polycomb protein EED