PDB 5trf

PDB Information

PDB5TRF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
Wang, S., Sun, W., Zhao, Y., McEachern, D., Meaux, I., Barriere, C., Stuckey, J.A., Meagher, J.L., Bai, L., Liu, L., Hoffman-Luca, C.G., Lu, J., Shangary, S., Yu, S., Bernard, D., Aguilar, A., Dos-Santos, O., Besret, L., Guerif, S., Pannier, P., Gorge-Bernat, D., Debussche, L.
Cancer Res.
HeaderLigase/Ligase Inhibitor
Released2016-10-26
Resolution2.100
CATH Insert Date20 Nov, 2016

PDB Images (11)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped
C 21 Nov, 2016 Chopped
D 21 Nov, 2016 Chopped
E 21 Nov, 2016 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
5trfA00 25 Nov, 2016 1.10.245.10 Assigned
5trfB00 25 Nov, 2016 1.10.245.10 Assigned
5trfC00 25 Nov, 2016 1.10.245.10 Assigned
5trfD00 25 Nov, 2016 1.10.245.10 Assigned
5trfE00 25 Nov, 2016 1.10.245.10 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2