PDB 5tgk

PDB Information

PDB5TGK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceHomo sapiens
Primary Citation
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.
Wang, C., Aleksandrov, A.A., Yang, Z., Forouhar, F., Proctor, E.A., Kota, P., An, J., Kaplan, A., Khazanov, N., Boel, G., Stockwell, B.R., Senderowitz, H., Dokholyan, N.V., Riordan, J.R., Brouillette, C.G., Hunt, J.F.
J. Biol. Chem.
HeaderHydrolase
Released2016-09-28
Resolution1.910
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5tgkA00 28 Jun, 2018 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P13569 CFTR_HUMAN Homo sapiens Cystic fibrosis transmembrane conductance regulator
CATH-Gene3D is a Global Biodata Core Resource Learn more...