PDB Information

PDB5TC0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate.
Keung, W., Boloor, A., Brown, J., Kiryanov, A., Gangloff, A., Lawson, J.D., Skene, R., Hoffman, I., Atienza, J., Kahana, J., De Jong, R., Farrell, P., Balakrishna, D., Halkowycz, P.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2016-09-13
Resolution2.240
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5tc0A01 21 May, 2017 Holding pen
5tc0A02 21 May, 2017 1.10.510.10 Assigned
5tc0B01 21 May, 2017 Holding pen
5tc0B02 21 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer