A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.
Phillips, M.A., White, K.L., Kokkonda, S., Deng, X., White, J., El Mazouni, F., Marsh, K., Tomchick, D.R., Manjalanagara, K., Rudra, K.R., Wirjanata, G., Noviyanti, R., Price, R.N., Marfurt, J., Shackleford, D.M., Chiu, F.C., Campbell, M., Jimenez-Diaz, M.B., Bazaga, S.F., Angulo-Barturen, I., Martinez, M.S., Lafuente-Monasterio, M., Kaminsky, W., Silue, K., Zeeman, A.M., Kocken, C., Leroy, D., Blasco, B., Rossignol, E., Rueckle, T., Matthews, D., Burrows, J.N., Waterson, D., Palmer, M.J., Rathod, P.K., Charman, S.A.
ACS Infect Dis