PDB 5t8f

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Overview

PDB Information

PDB	5T8F
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K). Castanedo, G.M., Blaquiere, N., Beresini, M., Bravo, B., Brightbill, H., Chen, J., Cui, H.F., Eigenbrot, C., Everett, C., Feng, J., Godemann, R., Gogol, E., Hymowitz, S., Johnson, A., Kayagaki, N., Kohli, P.B., Knuppel, K., Kraemer, J., Kruger, S., Loke, P., McEwan, P., Montalbetti, C., Roberts, D.A., Smith, M., Steinbacher, S., Sujatha-Bhaskar, S., Takahashi, R., Wang, X., Wu, L.C., Zhang, Y., Staben, S.T. J. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-09-07
Resolution	2.910
CATH Insert Date	07 May, 2017

PDB Images (3)

Image of CATH 5t8f

5t8f

PDB 5t8f

Image of CATH 5t8fA

5t8fA

PDB Chain 5t8fA

Image of CATH 5t8fB

5t8fB

PDB Chain 5t8fB

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Holding pen
B	08 May, 2017	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P23727	P85A_BOVIN	Bos taurus	Phosphatidylinositol 3-kinase regulatory subunit alpha
O00329	PK3CD_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform