PDB Information

PDB5T68
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Synthesis and optimization of furano[3,2-d]pyrimidines as selective spleen tyrosine kinase (Syk) inhibitors.
Hoemann, M., Wilson, N., Argiriadi, M., Banach, D., Burchat, A., Calderwood, D., Clapham, B., Cox, P., Duignan, D.B., Konopacki, D., Somal, G., Vasudevan, A.
Bioorg. Med. Chem. Lett.
HeaderTransferase/Transferase Inhibitor
Released2016-09-01
Resolution2.930
CATH Insert Date06 Nov, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped
B 07 Nov, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5t68A01 10 Nov, 2016 3.30.200.20 Assigned
5t68A02 10 Nov, 2016 1.10.510.10 Assigned
5t68B01 10 Nov, 2016 3.30.200.20 Assigned
5t68B02 10 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
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