PDB Information

PDB5SXN
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors.
Imaeda, Y., Tawada, M., Suzuki, S., Tomimoto, M., Kondo, M., Tarui, N., Sanada, T., Kanagawa, R., Snell, G., Behnke, C.A., Kubo, K., Kuroita, T.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-08-09
Resolution2.100
CATH Insert Date20 Nov, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5sxnA01 25 Nov, 2016 2.40.70.10 Assigned
5sxnA02 25 Nov, 2016 2.40.70.10 Assigned
5sxnB01 25 Nov, 2016 2.40.70.10 Assigned
5sxnB02 25 Nov, 2016 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin
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