PDB 5sxj

PDB Links
Overview

PDB Information

PDB	5SXJ
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B. Bioorg. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-08-09
Resolution	3.420
CATH Insert Date	21 May, 2017

PDB Images (5)

Image of CATH 5sxj

5sxj

PDB 5sxj

Image of CATH 5sxjA

5sxjA

PDB Chain 5sxjA

Image of CATH 5sxjB

5sxjB

PDB Chain 5sxjB

Image of CATH 5sxjB01

5sxjB01

CATH Domain 5sxjB01

Image of CATH 5sxjB02

5sxjB02

CATH Domain 5sxjB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	22 May, 2017	Holding pen
B	22 May, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5sxjB01	14 Nov, 2017		Holding pen
5sxjB02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform