PDB 5sxb

PDB Links
Overview

PDB Information

PDB	5SXB
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B. Bioorg. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-08-09
Resolution	3.300
CATH Insert Date	07 May, 2017

PDB Images (5)

Image of CATH 5sxb

5sxb

PDB 5sxb

Image of CATH 5sxbA

5sxbA

PDB Chain 5sxbA

Image of CATH 5sxbB

5sxbB

PDB Chain 5sxbB

Image of CATH 5sxbB01

5sxbB01

CATH Domain 5sxbB01

Image of CATH 5sxbB02

5sxbB02

CATH Domain 5sxbB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Holding pen
B	08 May, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5sxbB01	14 Nov, 2017		Holding pen
5sxbB02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform