PDB 5sxa

PDB Links
Overview

PDB Information

PDB	5SXA
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B. Bioorg. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-08-09
Resolution	3.350
CATH Insert Date	07 May, 2017

PDB Images (5)

Image of CATH 5sxa

5sxa

PDB 5sxa

Image of CATH 5sxaA

5sxaA

PDB Chain 5sxaA

Image of CATH 5sxaB

5sxaB

PDB Chain 5sxaB

Image of CATH 5sxaB01

5sxaB01

CATH Domain 5sxaB01

Image of CATH 5sxaB02

5sxaB02

CATH Domain 5sxaB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Holding pen
B	08 May, 2017	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5sxaB01	14 Nov, 2017		Holding pen
5sxaB02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform