PDB 5oq4

PDB Links
Overview

PDB Information

PDB	5OQ4
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. Beaufils, F., Cmiljanovic, N., Cmiljanovic, V., Bohnacker, T., Melone, A., Marone, R., Jackson, E., Zhang, X., Sele, A., Borsari, C., Mestan, J., Hebeisen, P., Hillmann, P., Giese, B., Zvelebil, M., Fabbro, D., Williams, R.L., Rageot, D., Wymann, M.P. J. Med. Chem.
Header	Transferase
Released	2017-08-10
Resolution	2.700
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5oq4

5oq4

PDB 5oq4

Image of CATH 5oq4A

5oq4A

PDB Chain 5oq4A

Image of CATH 5oq4A01

5oq4A01

CATH Domain 5oq4A01

Image of CATH 5oq4A02

5oq4A02

CATH Domain 5oq4A02

Image of CATH 5oq4A03

5oq4A03

CATH Domain 5oq4A03

Image of CATH 5oq4A04

5oq4A04

CATH Domain 5oq4A04

Image of CATH 5oq4A05

5oq4A05

CATH Domain 5oq4A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5oq4A01	10 Dec, 2017	3.10.20.90	Assigned
5oq4A02	10 Dec, 2017	2.60.40.150	Assigned
5oq4A03	10 Dec, 2017	1.25.40.70	Assigned
5oq4A04	10 Dec, 2017	3.30.1010.10	Assigned
5oq4A05	10 Dec, 2017	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform