PDB 5o4e

PDB Information

PDB5O4E
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
Lobner, E., Humm, A.S., Mlynek, G., Kubinger, K., Kitzmuller, M., Traxlmayr, M.W., Djinovic-Carugo, K., Obinger, C.
MAbs
HeaderImmune System
Released2017-05-29
Resolution2.150
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5o4eA01 16 Dec, 2017 Holding pen
5o4eA02 16 Dec, 2017 2.60.40.10 Assigned
5o4eB01 16 Dec, 2017 Holding pen
5o4eB02 16 Dec, 2017 2.60.40.10 Assigned
5o4eC01 16 Dec, 2017 Holding pen
5o4eC02 16 Dec, 2017 2.60.40.10 Assigned
5o4eD01 16 Dec, 2017 Holding pen
5o4eD02 16 Dec, 2017 2.60.40.10 Assigned
5o4eE00 10 Dec, 2017 2.10.90.10 Assigned
5o4eF00 10 Dec, 2017 2.10.90.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
P0DOX5 IGG1_HUMAN Homo sapiens Immunoglobulin gamma-1 heavy chain
P0DOX5 IGG1_HUMAN Homo sapiens Immunoglobulin gamma-1 heavy chain
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
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