PDB Information

PDB5NN0
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.
Kosak, U., Brus, B., Knez, D., Zakelj, S., Trontelj, J., Pislar, A., Sink, R., Jukic, M., Zivin, M., Podkowa, A., Nachon, F., Brazzolotto, X., Stojan, J., Kos, J., Coquelle, N., Salat, K., Colletier, J.P., Gobec, S.
J. Med. Chem.
HeaderHydrolase
Released2017-04-07
Resolution2.100
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5nn0A00 27 Jun, 2018 3.40.50.1820 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P06276 CHLE_HUMAN Homo sapiens Cholinesterase
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