PDB 5ni8

PDB Information

PDB5NI8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Potent and Orally Bioavailable Inverse Agonists of ROR gamma t Resulting from Structure-Based Design.
Narjes, F., Xue, Y., von Berg, S., Malmberg, J., Llinas, A., Olsson, R.I., Jirholt, J., Grindebacke, H., Leffler, A., Hossain, N., Lepisto, M., Thunberg, L., Leek, H., Aagaard, A., McPheat, J., Hansson, E.L., Back, E., Tangefjord, S., Chen, R., Xiong, Y., Hongbin, G., Hansson, T.G.
J. Med. Chem.
HeaderRar-Related Orphan Receptor-G (Rorg)
Released2017-03-23
Resolution1.940
CATH Insert Date26 Aug, 2018

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 26 Aug, 2018 Chopped
C 26 Aug, 2018 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5ni8A00 27 Aug, 2018 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2