PDB 5nhp

PDB Information

PDB5NHP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
Ward, R.A., Bethel, P., Cook, C., Davies, E., Debreczeni, J.E., Fairley, G., Feron, L., Flemington, V., Graham, M.A., Greenwood, R., Griffin, N., Hanson, L., Hopcroft, P., Howard, T.D., Hudson, J., James, M., Jones, C.D., Jones, C.R., Lamont, S., Lewis, R., Lindsay, N., Roberts, K., Simpson, I., St-Gallay, S., Swallow, S., Tang, J., Tonge, M., Wang, Z., Zhai, B.
J. Med. Chem.
HeaderTransferase
Released2017-03-22
Resolution1.990
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5nhpA01 18 May, 2017 3.30.200.20 Assigned
5nhpA02 18 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
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