PDB Information

PDB5NB6
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.
Lorthiois, E., Anderson, K., Vulpetti, A., Rogel, O., Cumin, F., Ostermann, N., Steinbacher, S., Mac Sweeney, A., Delgado, O., Liao, S.M., Randl, S., Rudisser, S., Dussauge, S., Fettis, K., Kieffer, L., de Erkenez, A., Yang, L., Hartwieg, C., Argikar, U.A., La Bonte, L.R., Newton, R., Kansara, V., Flohr, S., Hommel, U., Jaffee, B., Maibaum, J.
J. Med. Chem.
HeaderHydrolase
Released2017-03-01
Resolution1.750
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5nb6A01 10 Dec, 2017 2.40.10.10 Assigned
5nb6A02 10 Dec, 2017 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
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