PDB Information

PDB5MXA
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Bloch, Y., Bouchareychas, L., Merceron, R., Skladanowska, K., Van den Bossche, L., Detry, S., Govindarajan, S., Elewaut, D., Haerynck, F., Dullaers, M., Adamopoulos, I.E., Savvides, S.N.
Immunity
HeaderCytokine
Released2017-01-22
Resolution2.500
CATH Insert Date07 Jan, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Jan, 2018 Chopped
B 07 Jan, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5mxaA01 11 Jan, 2018 2.60.40.10 Assigned
5mxaA02 11 Jan, 2018 2.60.40.10 Assigned
5mxaA03 11 Jan, 2018 2.60.40.10 Assigned
5mxaB00 11 Jan, 2018 1.20.1250.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29460 IL12B_HUMAN Homo sapiens Interleukin-12 subunit beta
Q9NPF7 IL23A_HUMAN Homo sapiens Interleukin-23 subunit alpha
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