PDB 5ml8

PDB Information

PDB5ML8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A PDE6 delta-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2.
Martin-Gago, P., Fansa, E.K., Klein, C.H., Murarka, S., Janning, P., Schurmann, M., Metz, M., Ismail, S., Schultz-Fademrecht, C., Baumann, M., Bastiaens, P.I., Wittinghofer, A., Waldmann, H.
Angew. Chem. Int. Ed. Engl.
HeaderLipid Binding Protein
Released2016-12-06
Resolution2.600
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
B 08 May, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5ml8B00 16 May, 2017 2.70.50.40 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O43924 PDE6D_HUMAN Homo sapiens Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
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