PDB 5m32

PDB Links
Overview

PDB Information

PDB	5M32
Method	ELECTRON MICROSCOPY
Host Organism
Gene Source
Primary Citation	Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Haselbach, D., Schrader, J., Lambrecht, F., Henneberg, F., Chari, A., Stark, H. Nat Commun
Header	Hydrolase
Released	2016-10-14
Resolution	3.800
CATH Insert Date	14 Nov, 2017

PDB Images (78)

5m32

PDB 5m32

5m32a

PDB Chain 5m32a

5m32A

PDB Chain 5m32A

5m32b

PDB Chain 5m32b

5m32B

PDB Chain 5m32B

5m32c

PDB Chain 5m32c

5m32C

PDB Chain 5m32C

5m32d

PDB Chain 5m32d

5m32D

PDB Chain 5m32D

5m32e

PDB Chain 5m32e

5m32E

PDB Chain 5m32E

5m32f

PDB Chain 5m32f

5m32F

PDB Chain 5m32F

5m32g

PDB Chain 5m32g

5m32G

PDB Chain 5m32G

5m32h

PDB Chain 5m32h

5m32H

PDB Chain 5m32H

5m32i

PDB Chain 5m32i

5m32I

PDB Chain 5m32I

5m32j

PDB Chain 5m32j

5m32J

PDB Chain 5m32J

5m32k

PDB Chain 5m32k

5m32K

PDB Chain 5m32K

5m32l

PDB Chain 5m32l

5m32L

PDB Chain 5m32L

5m32m

PDB Chain 5m32m

5m32M

PDB Chain 5m32M

5m32n

PDB Chain 5m32n

5m32N

PDB Chain 5m32N

5m32o

PDB Chain 5m32o

5m32O

PDB Chain 5m32O

5m32p

PDB Chain 5m32p

5m32P

PDB Chain 5m32P

5m32q

PDB Chain 5m32q

5m32Q

PDB Chain 5m32Q

5m32r

PDB Chain 5m32r

5m32R

PDB Chain 5m32R

5m32s

PDB Chain 5m32s

5m32S

PDB Chain 5m32S

5m32T

PDB Chain 5m32T

5m32U

PDB Chain 5m32U

5m32V

PDB Chain 5m32V

5m32W

PDB Chain 5m32W

5m32X

PDB Chain 5m32X

5m32Y

PDB Chain 5m32Y

5m32Z

PDB Chain 5m32Z

5m32a00

CATH Domain 5m32a00

5m32A00

CATH Domain 5m32A00

5m32b00

CATH Domain 5m32b00

5m32B00

CATH Domain 5m32B00

5m32C00

CATH Domain 5m32C00

5m32D00

CATH Domain 5m32D00

5m32E00

CATH Domain 5m32E00

5m32F00

CATH Domain 5m32F00

5m32G00

CATH Domain 5m32G00

5m32H00

CATH Domain 5m32H00

5m32h01

CATH Domain 5m32h01

5m32h02

CATH Domain 5m32h02

5m32h03

CATH Domain 5m32h03

5m32I00

CATH Domain 5m32I00

5m32J00

CATH Domain 5m32J00

5m32K00

CATH Domain 5m32K00

5m32L00

CATH Domain 5m32L00

5m32M00

CATH Domain 5m32M00

5m32N00

CATH Domain 5m32N00

5m32O00

CATH Domain 5m32O00

5m32p00

CATH Domain 5m32p00

5m32P00

CATH Domain 5m32P00

5m32Q00

CATH Domain 5m32Q00

5m32R00

CATH Domain 5m32R00

5m32S00

CATH Domain 5m32S00

5m32T00

CATH Domain 5m32T00

5m32U00

CATH Domain 5m32U00

5m32V00

CATH Domain 5m32V00

5m32W00

CATH Domain 5m32W00

5m32X00

CATH Domain 5m32X00

5m32Y00

CATH Domain 5m32Y00

5m32Z00

CATH Domain 5m32Z00

PDB Prints

PDB Chains (45)

Chain ID	Date inserted into CATH	CATH Status
a	14 Nov, 2017	Chopped
A	14 Nov, 2017	Chopped
b	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
c	14 Nov, 2017	Holding pen
C	14 Nov, 2017	Chopped
d	14 Nov, 2017	Holding pen
D	14 Nov, 2017	Chopped
e	14 Nov, 2017	Holding pen
E	14 Nov, 2017	Chopped
f	14 Nov, 2017	Domchop review
F	14 Nov, 2017	Chopped
g	14 Nov, 2017	Holding pen
G	14 Nov, 2017	Chopped
h	14 Nov, 2017	Chopped
H	14 Nov, 2017	Chopped
i	14 Nov, 2017	Domchop review
I	14 Nov, 2017	Chopped
j	14 Nov, 2017	Domchop review
J	14 Nov, 2017	Chopped
k	14 Nov, 2017	Domchop review
K	14 Nov, 2017	Chopped
l	14 Nov, 2017	Domchop review
L	14 Nov, 2017	Chopped
m	14 Nov, 2017	Domchop review
M	14 Nov, 2017	Chopped
n	14 Nov, 2017	Domchop review
N	14 Nov, 2017	Chopped
o	14 Nov, 2017	Domchop allotted
O	14 Nov, 2017	Chopped
p	14 Nov, 2017	Chopped
P	14 Nov, 2017	Chopped
q	14 Nov, 2017	Domchop review
Q	14 Nov, 2017	Chopped
r	14 Nov, 2017	Rejected
R	14 Nov, 2017	Chopped
s	14 Nov, 2017	Rejected
S	14 Nov, 2017	Chopped
T	14 Nov, 2017	Chopped
U	14 Nov, 2017	Chopped
V	14 Nov, 2017	Chopped
W	14 Nov, 2017	Chopped
X	14 Nov, 2017	Chopped
Y	14 Nov, 2017	Chopped
Z	14 Nov, 2017	Chopped

CATH Domains (32)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5m32a00	10 Dec, 2017	3.60.20.10	Assigned
5m32A00	10 Dec, 2017	3.60.20.10	Assigned
5m32b00	10 Dec, 2017	3.60.20.10	Assigned
5m32B00	10 Dec, 2017	3.60.20.10	Assigned
5m32C00	10 Dec, 2017	3.60.20.10	Assigned
5m32D00	10 Dec, 2017	3.60.20.10	Assigned
5m32E00	10 Dec, 2017	3.60.20.10	Assigned
5m32F00	10 Dec, 2017	3.60.20.10	Assigned
5m32G00	10 Dec, 2017	3.60.20.10	Assigned
5m32H00	10 Dec, 2017	3.60.20.10	Assigned
5m32h01	05 Apr, 2018		Write scan list
5m32h02	05 Apr, 2018	3.40.50.300	Assigned
5m32h03	05 Apr, 2018	1.10.8.60	Assigned
5m32I00	10 Dec, 2017	3.60.20.10	Assigned
5m32J00	10 Dec, 2017	3.60.20.10	Assigned
5m32K00	10 Dec, 2017	3.60.20.10	Assigned
5m32L00	10 Dec, 2017	3.60.20.10	Assigned
5m32M00	10 Dec, 2017	3.60.20.10	Assigned
5m32N00	10 Dec, 2017	3.60.20.10	Assigned
5m32O00	10 Dec, 2017	3.60.20.10	Assigned
5m32p00	16 Dec, 2017		Write scan list
5m32P00	10 Dec, 2017	3.60.20.10	Assigned
5m32Q00	10 Dec, 2017	3.60.20.10	Assigned
5m32R00	10 Dec, 2017	3.60.20.10	Assigned
5m32S00	10 Dec, 2017	3.60.20.10	Assigned
5m32T00	10 Dec, 2017	3.60.20.10	Assigned
5m32U00	10 Dec, 2017	3.60.20.10	Assigned
5m32V00	10 Dec, 2017	3.60.20.10	Assigned
5m32W00	10 Dec, 2017	3.60.20.10	Assigned
5m32X00	10 Dec, 2017	3.60.20.10	Assigned
5m32Y00	10 Dec, 2017	3.60.20.10	Assigned
5m32Z00	10 Dec, 2017	3.60.20.10	Assigned

UniProtKB Entries (43)

Accession	Gene ID	Taxon	Description
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
Q15008	PSMD6_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 6
Q99460	PSMD1_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 1
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P62191	PRS4_HUMAN	Homo sapiens	26S proteasome regulatory subunit 4
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
O43242	PSMD3_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 3
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P48556	PSMD8_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 8
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P62333	PRS10_HUMAN	Homo sapiens	26S proteasome regulatory subunit 10B
P62195	PRS8_HUMAN	Homo sapiens	26S proteasome regulatory subunit 8
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P43686	PRS6B_HUMAN	Homo sapiens	26S proteasome regulatory subunit 6B
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P17980	PRS6A_HUMAN	Homo sapiens	26S proteasome regulatory subunit 6A
O00231	PSD11_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 11
O00487	PSDE_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 14
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P55036	PSMD4_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 4
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
O00232	PSD12_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 12
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P51665	PSMD7_HUMAN	Homo sapiens	26S proteasome non-ATPase regulatory subunit 7
P35998	PRS7_HUMAN	Homo sapiens	26S proteasome regulatory subunit 7
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4