PDB 5lz8

PDB Information

PDB5LZ8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).
Woolford, A.J., Day, P.J., Beneton, V., Berdini, V., Coyle, J.E., Dudit, Y., Grondin, P., Huet, P., Lee, L.Y., Manas, E.S., McMenamin, R.L., Murray, C.W., Page, L.W., Patel, V.K., Potvain, F., Rich, S.J., Sang, Y., Somers, D.O., Trottet, L., Wan, Z., Zhang, X.
J. Med. Chem.
HeaderHydrolase
Released2016-09-29
Resolution2.110
CATH Insert Date25 Dec, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 Dec, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5lz8A00 30 Dec, 2016 3.40.50.1820 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q13093 PAFA_HUMAN Homo sapiens Platelet-activating factor acetylhydrolase
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