PDB 5lvx

PDB Information

PDB5LVX
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.
Zheng, J., Chen, L., Skinner, O.S., Ysselstein, D., Remis, J., Lansbury, P., Skerlj, R., Mrosek, M., Heunisch, U., Krapp, S., Charrow, J., Schwake, M., Kelleher, N.L., Silverman, R.B., Krainc, D.
J. Am. Chem. Soc.
HeaderHydrolase
Released2016-09-14
Resolution2.200
CATH Insert Date14 Nov, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5lvxA01 10 Dec, 2017 3.20.20.80 Assigned
5lvxA02 10 Dec, 2017 2.60.40.1180 Assigned
5lvxB01 10 Dec, 2017 3.20.20.80 Assigned
5lvxB02 10 Dec, 2017 2.60.40.1180 Assigned
5lvxC01 10 Dec, 2017 3.20.20.80 Assigned
5lvxC02 10 Dec, 2017 2.60.40.1180 Assigned
5lvxD01 10 Dec, 2017 3.20.20.80 Assigned
5lvxD02 10 Dec, 2017 2.60.40.1180 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase