PDB Information

PDB5LMA
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Garton, N.S., Barker, M.D., Davis, R.P., Douault, C., Hooper-Greenhill, E., Jones, E., Lewis, H.D., Liddle, J., Lugo, D., McCleary, S., Preston, A.G., Ramirez-Molina, C., Neu, M., Shipley, T.J., Somers, D.O., Watson, R.J., Wilson, D.M.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2016-07-29
Resolution1.430
CATH Insert Date02 Oct, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5lmaA01 07 Oct, 2016 3.30.200.20 Assigned
5lmaA02 07 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
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