PDB 5lez

PDB Links
Overview

PDB Information

PDB	5LEZ
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Schrader, J., Henneberg, F., Mata, R.A., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A. Science
Header	Hydrolase
Released	2016-06-30
Resolution	2.190
CATH Insert Date	04 Sep, 2016

PDB Images (57)

5lez

PDB 5lez

5leza

PDB Chain 5leza

5lezA

PDB Chain 5lezA

5lezb

PDB Chain 5lezb

5lezB

PDB Chain 5lezB

5lezC

PDB Chain 5lezC

5lezD

PDB Chain 5lezD

5lezE

PDB Chain 5lezE

5lezF

PDB Chain 5lezF

5lezG

PDB Chain 5lezG

5lezH

PDB Chain 5lezH

5lezI

PDB Chain 5lezI

5lezJ

PDB Chain 5lezJ

5lezK

PDB Chain 5lezK

5lezL

PDB Chain 5lezL

5lezM

PDB Chain 5lezM

5lezN

PDB Chain 5lezN

5lezO

PDB Chain 5lezO

5lezP

PDB Chain 5lezP

5lezQ

PDB Chain 5lezQ

5lezR

PDB Chain 5lezR

5lezS

PDB Chain 5lezS

5lezT

PDB Chain 5lezT

5lezU

PDB Chain 5lezU

5lezV

PDB Chain 5lezV

5lezW

PDB Chain 5lezW

5lezX

PDB Chain 5lezX

5lezY

PDB Chain 5lezY

5lezZ

PDB Chain 5lezZ

5leza00

CATH Domain 5leza00

5lezA00

CATH Domain 5lezA00

5lezb00

CATH Domain 5lezb00

5lezB00

CATH Domain 5lezB00

5lezC00

CATH Domain 5lezC00

5lezD00

CATH Domain 5lezD00

5lezE00

CATH Domain 5lezE00

5lezF00

CATH Domain 5lezF00

5lezG00

CATH Domain 5lezG00

5lezH00

CATH Domain 5lezH00

5lezI00

CATH Domain 5lezI00

5lezJ00

CATH Domain 5lezJ00

5lezK00

CATH Domain 5lezK00

5lezL00

CATH Domain 5lezL00

5lezM00

CATH Domain 5lezM00

5lezN00

CATH Domain 5lezN00

5lezO00

CATH Domain 5lezO00

5lezP00

CATH Domain 5lezP00

5lezQ00

CATH Domain 5lezQ00

5lezR00

CATH Domain 5lezR00

5lezS00

CATH Domain 5lezS00

5lezT00

CATH Domain 5lezT00

5lezU00

CATH Domain 5lezU00

5lezV00

CATH Domain 5lezV00

5lezW00

CATH Domain 5lezW00

5lezX00

CATH Domain 5lezX00

5lezY00

CATH Domain 5lezY00

5lezZ00

CATH Domain 5lezZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	05 Sep, 2016	Chopped
A	05 Sep, 2016	Chopped
b	05 Sep, 2016	Chopped
B	05 Sep, 2016	Chopped
C	05 Sep, 2016	Chopped
D	05 Sep, 2016	Chopped
E	05 Sep, 2016	Chopped
F	05 Sep, 2016	Chopped
G	05 Sep, 2016	Chopped
H	05 Sep, 2016	Chopped
I	05 Sep, 2016	Chopped
J	05 Sep, 2016	Chopped
K	05 Sep, 2016	Chopped
L	05 Sep, 2016	Chopped
M	05 Sep, 2016	Chopped
N	05 Sep, 2016	Chopped
O	05 Sep, 2016	Chopped
P	05 Sep, 2016	Chopped
Q	05 Sep, 2016	Chopped
R	05 Sep, 2016	Chopped
S	05 Sep, 2016	Chopped
T	05 Sep, 2016	Chopped
U	05 Sep, 2016	Chopped
V	05 Sep, 2016	Chopped
W	05 Sep, 2016	Chopped
X	05 Sep, 2016	Chopped
Y	05 Sep, 2016	Chopped
Z	05 Sep, 2016	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5leza00	09 Sep, 2016	3.60.20.10	Assigned
5lezA00	09 Sep, 2016	3.60.20.10	Assigned
5lezb00	20 Oct, 2016	3.60.20.10	Assigned
5lezB00	09 Sep, 2016	3.60.20.10	Assigned
5lezC00	09 Sep, 2016	3.60.20.10	Assigned
5lezD00	09 Sep, 2016	3.60.20.10	Assigned
5lezE00	09 Sep, 2016	3.60.20.10	Assigned
5lezF00	09 Sep, 2016	3.60.20.10	Assigned
5lezG00	09 Sep, 2016	3.60.20.10	Assigned
5lezH00	09 Sep, 2016	3.60.20.10	Assigned
5lezI00	09 Sep, 2016	3.60.20.10	Assigned
5lezJ00	09 Sep, 2016	3.60.20.10	Assigned
5lezK00	09 Sep, 2016	3.60.20.10	Assigned
5lezL00	09 Sep, 2016	3.60.20.10	Assigned
5lezM00	09 Sep, 2016	3.60.20.10	Assigned
5lezN00	20 Oct, 2016	3.60.20.10	Assigned
5lezO00	09 Sep, 2016	3.60.20.10	Assigned
5lezP00	09 Sep, 2016	3.60.20.10	Assigned
5lezQ00	09 Sep, 2016	3.60.20.10	Assigned
5lezR00	09 Sep, 2016	3.60.20.10	Assigned
5lezS00	09 Sep, 2016	3.60.20.10	Assigned
5lezT00	09 Sep, 2016	3.60.20.10	Assigned
5lezU00	09 Sep, 2016	3.60.20.10	Assigned
5lezV00	09 Sep, 2016	3.60.20.10	Assigned
5lezW00	09 Sep, 2016	3.60.20.10	Assigned
5lezX00	09 Sep, 2016	3.60.20.10	Assigned
5lezY00	09 Sep, 2016	3.60.20.10	Assigned
5lezZ00	09 Sep, 2016	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3