PDB 5lex

PDB Links
Overview

PDB Information

PDB	5LEX
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Schrader, J., Henneberg, F., Mata, R.A., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A. Science
Header	Hydrolase
Released	2016-06-30
Resolution	2.200
CATH Insert Date	04 Sep, 2016

PDB Images (57)

5lex

PDB 5lex

5lexa

PDB Chain 5lexa

5lexA

PDB Chain 5lexA

5lexb

PDB Chain 5lexb

5lexB

PDB Chain 5lexB

5lexC

PDB Chain 5lexC

5lexD

PDB Chain 5lexD

5lexE

PDB Chain 5lexE

5lexF

PDB Chain 5lexF

5lexG

PDB Chain 5lexG

5lexH

PDB Chain 5lexH

5lexI

PDB Chain 5lexI

5lexJ

PDB Chain 5lexJ

5lexK

PDB Chain 5lexK

5lexL

PDB Chain 5lexL

5lexM

PDB Chain 5lexM

5lexN

PDB Chain 5lexN

5lexO

PDB Chain 5lexO

5lexP

PDB Chain 5lexP

5lexQ

PDB Chain 5lexQ

5lexR

PDB Chain 5lexR

5lexS

PDB Chain 5lexS

5lexT

PDB Chain 5lexT

5lexU

PDB Chain 5lexU

5lexV

PDB Chain 5lexV

5lexW

PDB Chain 5lexW

5lexX

PDB Chain 5lexX

5lexY

PDB Chain 5lexY

5lexZ

PDB Chain 5lexZ

5lexa00

CATH Domain 5lexa00

5lexA00

CATH Domain 5lexA00

5lexb00

CATH Domain 5lexb00

5lexB00

CATH Domain 5lexB00

5lexC00

CATH Domain 5lexC00

5lexD00

CATH Domain 5lexD00

5lexE00

CATH Domain 5lexE00

5lexF00

CATH Domain 5lexF00

5lexG00

CATH Domain 5lexG00

5lexH00

CATH Domain 5lexH00

5lexI00

CATH Domain 5lexI00

5lexJ00

CATH Domain 5lexJ00

5lexK00

CATH Domain 5lexK00

5lexL00

CATH Domain 5lexL00

5lexM00

CATH Domain 5lexM00

5lexN00

CATH Domain 5lexN00

5lexO00

CATH Domain 5lexO00

5lexP00

CATH Domain 5lexP00

5lexQ00

CATH Domain 5lexQ00

5lexR00

CATH Domain 5lexR00

5lexS00

CATH Domain 5lexS00

5lexT00

CATH Domain 5lexT00

5lexU00

CATH Domain 5lexU00

5lexV00

CATH Domain 5lexV00

5lexW00

CATH Domain 5lexW00

5lexX00

CATH Domain 5lexX00

5lexY00

CATH Domain 5lexY00

5lexZ00

CATH Domain 5lexZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	05 Sep, 2016	Chopped
A	05 Sep, 2016	Chopped
b	05 Sep, 2016	Chopped
B	05 Sep, 2016	Chopped
C	05 Sep, 2016	Chopped
D	05 Sep, 2016	Chopped
E	05 Sep, 2016	Chopped
F	05 Sep, 2016	Chopped
G	05 Sep, 2016	Chopped
H	05 Sep, 2016	Chopped
I	05 Sep, 2016	Chopped
J	05 Sep, 2016	Chopped
K	05 Sep, 2016	Chopped
L	05 Sep, 2016	Chopped
M	05 Sep, 2016	Chopped
N	05 Sep, 2016	Chopped
O	05 Sep, 2016	Chopped
P	05 Sep, 2016	Chopped
Q	05 Sep, 2016	Chopped
R	05 Sep, 2016	Chopped
S	05 Sep, 2016	Chopped
T	05 Sep, 2016	Chopped
U	05 Sep, 2016	Chopped
V	05 Sep, 2016	Chopped
W	05 Sep, 2016	Chopped
X	05 Sep, 2016	Chopped
Y	05 Sep, 2016	Chopped
Z	05 Sep, 2016	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5lexa00	09 Sep, 2016	3.60.20.10	Assigned
5lexA00	09 Sep, 2016	3.60.20.10	Assigned
5lexb00	20 Oct, 2016	3.60.20.10	Assigned
5lexB00	09 Sep, 2016	3.60.20.10	Assigned
5lexC00	09 Sep, 2016	3.60.20.10	Assigned
5lexD00	09 Sep, 2016	3.60.20.10	Assigned
5lexE00	09 Sep, 2016	3.60.20.10	Assigned
5lexF00	09 Sep, 2016	3.60.20.10	Assigned
5lexG00	09 Sep, 2016	3.60.20.10	Assigned
5lexH00	09 Sep, 2016	3.60.20.10	Assigned
5lexI00	09 Sep, 2016	3.60.20.10	Assigned
5lexJ00	09 Sep, 2016	3.60.20.10	Assigned
5lexK00	09 Sep, 2016	3.60.20.10	Assigned
5lexL00	09 Sep, 2016	3.60.20.10	Assigned
5lexM00	09 Sep, 2016	3.60.20.10	Assigned
5lexN00	20 Oct, 2016	3.60.20.10	Assigned
5lexO00	09 Sep, 2016	3.60.20.10	Assigned
5lexP00	09 Sep, 2016	3.60.20.10	Assigned
5lexQ00	09 Sep, 2016	3.60.20.10	Assigned
5lexR00	09 Sep, 2016	3.60.20.10	Assigned
5lexS00	09 Sep, 2016	3.60.20.10	Assigned
5lexT00	09 Sep, 2016	3.60.20.10	Assigned
5lexU00	09 Sep, 2016	3.60.20.10	Assigned
5lexV00	09 Sep, 2016	3.60.20.10	Assigned
5lexW00	09 Sep, 2016	3.60.20.10	Assigned
5lexX00	09 Sep, 2016	3.60.20.10	Assigned
5lexY00	09 Sep, 2016	3.60.20.10	Assigned
5lexZ00	09 Sep, 2016	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1